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The NF Preclinical Consortium is a $4M investment of the Childrens Tumor Foundation.

A multi-site collaboration of six research Centers, each focused on different tumor manifestations of NF1 and NF2,
the Centers of the Consortium began working together in 2008.

They are testing candidate NF drugs in parallel in multiple NF tumor models.

Industry collaborators to date include Novartis, Genetech and Avila Therapeutics.

NF Preclinical Consortium Centers 
University of California, San Francisco
Director: Kevin Shannon, MD, Ph.D.
Tumor Focus:  NF1 myeloid leukemia

Washington University School of Medicine
Director: David Gutmann, MD, Ph.D.
Tumor Focus:  NF1 optic pathway glioma          

Cincinnati Children’s Hospital Medical Center
Director: Timothy Cripe, MD, Ph.D.
Deputy Director: Nancy Ratner, Ph.D.
Tumor Focus: NF1 plexiform tumors & dermal neurofibromas

House Ear Institute
Director: Marco Giovannini, MD, Ph.D.
Tumor Focus: NF2 schwannoma, meningioma
                                                                                                                                                                                                                           
Harvard Med School/Mass General Hospital
Director: Andrea McClatchey, Ph.D.
Tumor Focus: NF2 schwannoma, meningioma   

Harvard Medical School/Brigham & Women’s Hospital
Director: Karen Cichowski, Ph.D.                   
Deputy Directors: Thomas De Raedt, Ph.D. & Ophelia Maertens, Ph.D.
Tumor Focus: NF1 malignant peripheral nerve sheath tumors     

NF Preclinical Consortium External Advisory Board (EAB)
 
Jay Gibbs, Ph.D. (Chair), AstraZeneca Pharmaceuticals

Gideon E. Bollag, Ph.D., Plexxikon Inc.

Sara A. Courtneidge, Ph.D. , The Burnham Inst. for Medical Research

Michael J. Morin, Ph.D., Oncovia, Inc.

Frank McCormick, Ph.D., University of California, San Francisco

Edward Stern, Esq.,  Legal Counel to the CTF Medical Advisory Committee

EAB Emeritus Members

Larry Gelbert, Ph.D., Eli Lilly and Company 

Filippo G. Giancotti, M.D., Ph.D. Memorial Sloan-Kettering Cancer Center

Janet M Hock, BDS, Ph.D., Maine Institute for Human Genetics and Health

Christopher L. Moertel, MD, Children's Hospitals and Clinics of Minnesota

Roger J. Packer, MD, Children’s National Medical Center

Questions? Contact:
Kim Hunter-Schaedle, Ph.D., Chief Scientific Officer
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