MRI bright spots ( and please someone w/more knowledge correct me ) are areas of HIGH-SIGNAL-INTENSITIES - the "physical" indications are that the "only" physical irregularity of the brain tissue at the location of the UBO is "a little more intra-cellular (between the cells) fluid/water. I believe this has to do w/growth rates of the brain tissue as affected by the gene-deletion that is NF. The areas of high signal intensity "COULD" represent the failure of the NF patients' brain to properly process or normally deal with "brain signals" where at the point where the UBO is found...the neurons are having a hard time allowing the "thought" or nerve signal to pass or "process" and because of the failure of the signal to smoothly "get through" the signal kind of "corrupts" and adjoining neurons attempt to properly process the signal. Meaning that as a signal is transmitted - it reaches a bottleneck, and as the signal continues it creates an area of neurons that are firing-off signals or "their own interpretations and attempts" of the signal that didn't quite get through or processed correctly.
An analogy ( like, but not exactly the same ) can be found in comparisson to epilepsy - where the UBO represents a "fire-storm" of signals all at the same time - though over larger portions of the brain.
I think that some researchers think that these areas where you find UBO's in NF patients are areas that in the end - are areas/parts of the brain where the processes of normal functioning are being disrupted and ultimately responsible for Non-Verbal Learning Disorders.
Beyond that what I can report that I have learned is that UBO's seem to "disappear" and quietly go away....as the person reaches adulthood. That the "localized" firestorms of neuronal activity represented by UBO's eventually train the childs' brain to "get the process complete" to "process the signal" that's having a hard time getting thru.
Imagine it this way. Lets say a child is walking to school. Pointed in the right direction, mommy sends him off walking towards the school w/a pat on the back. The most direct route though is blocked ( unbenounced to his parents ) by road construction. So faced with the obstacle, the child ( the signal ) trys all the alternate routes available at the location the roadblock is found. The child trys the alleys, the next street over ( in both directions ) and the alleys in between....all trying to reach the school. Eventually the signal gets through - the kid reaches school....but did he make it there without impediment? No. something along the path interferred with his ability to "go directly to school"....that being the resultant extra-fluid/water between the cells ...resultant from the not quite right "rates of growth" of brain tissue found in NF folks....
Think about your ability to express yourself. You know when you have exactly the idea that you want to convey....but for some reason it's not quite comming out as clearly as you invision the idea....kind of like a "fog" around the idea....like a haze of electrical signals pushing through to get whatever understanding the brain normally makes of the stimulus. There is an imparement there but the only identifiability is through what scientists know of brain-function in corellation with the location of the UBO.
Ask your Dr. to identify the locations of the UBO's and to corelate the locations w/typical brain function at those locations. They may correlate with communication-processing....resulting in the Attention-Deficit-Disorder....is the kid processing what he's seeing on the blackboard properly? does the same deficit occur when material is delivered instead in another format ( spoken word vs. written ideas on the black board ).
Im no doctor although I have a strong med background & a good science edu. all these ideas are what I have conveyed to you based upon my readings of the research I can find on the web or else where and my understandings of them.